Integrating Non-Covalent BTK Inhibitors in CLL: Navigating a Rapidly Evolving Treatment Landscape

Released September 4, 2024

In this episode, Dr. Versha Banerji discusses the potential impact of non-covalent BTKis for the treatment of CLL. 

UPDATES from eha 2024 - TREATMENT OF CLL

Released July 2, 2024

In this episode, Dr. Versha Banerji, Dr. Sarit Assouline, and Dr. Christopher Hillis discuss highlights from EHA 2024 on the treatment of CLL. 

LIVE from eha 2024 - sonrotoclax + Zanubrutinib in RR CLL

Released June 18, 2024

In this episode, Dr. Stephen Opat discusses the BGB-11417-101 study looking at sonrotoclax + zanubrutinib for the treatment RR CLL. 

CUTTING EDGE ADVANCES IN THE TREATMENT OF LUNG CANCER

Released April 24 2024

In this episode, Dr. Barbara Melosky discusses cutting edge approaches to the treatment of Lung Cancer, including the use of artificial intelligence and novel therapeutic approaches such as cancer vaccines and new targeted therapies.

precision medicine series ep15: BIOMARKERS IN UPper gi Cancer

Released April 18 2024

In this episode, Dr. Brezden-Masley (medical oncologist) and Dr. Streutker (pathologist) discuss the latest biomarkers that may inform treatment of upper GI cancer. 

Management of cSCC: A Surgeon’s Perspective

Released March 25 2024

In this episode, Dr. Mark Taylor discusses the surgical implications for the treatment of cSCC. 

Immunotherapy for Kidney Transplant Patients with Skin Cancer

Released March 25 2024

In this episode, Dr. Evan Lipson discusses the use of immunotherapy for patients with skin cancer who have had a kidney transplant. 

LIVE FROM ASH: Isa-CBD in ND Transplant eligible MM

Released December 18 2023

In this episode, Dr. Rami Kotb and Dr Donna Reece discuss results of the CMRG Isa-CYBORD trial presented at the ASH 2023.

LIVE FROM ASH: UPDATES ON THE ALPINE TRIAL

Released December 11 2023

In this episode, Dr. Jennifer Brown discusses updated results from the ALPINE trial of zanubrutinib vs ibrutinib for the treatment of CLL.

First Line la/mUC Evolving Treatment Strategies: S2 Ep 5 - ESMO 2023: 1L LA mUC

Released October 26 2023

In this fifth episode, Dr. Thomas Powles, Dr. Normand Blais, Dr. Srikala Sridhar, and Dr. Bernie Eigl, discuss the impact of new data from trials on 1L LA/mUC at ESMO 

First Line la/mUC Evolving Treatment Strategies: S2 Ep 4 - ROUND TABLE DISCUSSION -

Released October 12 2023

In this fourth episode taken from the UC webinar, Drs Normand Blais, Terence Friedlander, and Srikala Sridhar provide their perspective in a round table discussion. 

First Line la/mUC Evolving Treatment Strategies: S2 Ep 3 - CASE DISCUSSION

Released October 10 2023

This episode with Dr. Srikala Sridhar presents a clinical case on the treatment of la/mUC.

First Line la/mUC Evolving Treatment Strategies: S2 Ep 2 - 1L Treatment

Released October 5 2023

This episode with Dr. Normand Blais discusses the unmet treatment needs for la/mUC in the 1L setting in Canada.

First Line la/mUC Evolving Treatment Strategies: S2 Ep 1 - Unmet Needs

Released September 28 2023

This episode with Dr. Normand Blais discusses the unmet treatment needs for la/mUC in the 1L setting in Canada.

Urothelial Carcinoma: Management of Enfortumab Vedotin Adverse Events - S1 EP4: hyperglycemia

Released June 19 2023

This episode with Dr. Nimira Alimohamed and Dr. Minna Woo discusses the management of hyperglycemia with the use of EV in the treatment of patients with la/mUC.

precision medicine series ep14: EQA in biomarker testing

Released June 19 2023

This episode with Dr. Emina Torlakovic discusses the role of external quality assurance in improving the quality of biomarker assays in oncology. 

NMOSD Your WAY

Released May 2023

This podcast series hosted by NMOSD patients, Lelainia Lloyd and Debbie Leticq is an education series for NMOSD patients worldwide. 

Urothelial Carcinoma: Management of Enfortumab Vedotin Adverse Events - S1 EP3: peripheral neuropathy

Released May 15 2023

In this episode hosted by Dr Srikala Sridhar, Dr Warren Mason discusses the management of peripheral neiuropathy with EV in the treatment of patients with la/mUC. 

Urothelial Carcinoma: Management of Enfortumab Vedotin Adverse Events - S1 EP2: Skin reactions

Released April 28 2023

In this episode hosted by Dr Normand Blais, Dr Joel Claveau discusses the management of skin reactions with EV in the treatment of patients with la/mUC. 

Urothelial Carcinoma: Management of Enfortumab Vedotin Adverse Events - S1 EP1: Introduction to EV

Released April 28 2023

In this episode, Dr Normand Blais introduces the use of EV for the treatment of patients with la/mUC in a discussion with Dr Joel Claveau. 
Transcript_Panel Discussion. CCOLD.pdf

LIVE FROM CCOLD: CLL PANEL DISCUSSION

Released April 3 2023

In this episode, we talk with Dr. Laurie Sehn, Dr. Matthew Davids, and Dr. Constantine Tam live from the CCOLD meeting in Banff, AB about the treatment of CLL. Transcript available.

LIVE FROM CCOLD: TREATMENT OF CLL

Released March 25, 2023

In this episode, we talk with Dr. Matthew Davids live from the CCOLD meeting in Banff, AB about the treatment of CLL. 

Precision medicine series ep13: biomarkers in endometrial cancer

Released March 13, 2023

In this episode, we talk with Dr. Jessica McAlpine (gynecological oncologist) and Dr. Mary Kinloch (pathologist) about current and future biomarkers for the treatment of endometrial cancer. 

canadian perspective: alpine trial - zanubrutinib vs ibrutinib in cll

Released December 19, 2022

In this episode, we talk with Dr. Laurie Sehn about the impact on Canadian practice of the results of the ALPINE trial comparing zanubrutinib to ibrutinib for the treatment of CLL. 

live from ash: alpine trial - zanubrutinib vs ibrutinib in cll

Released December 14, 2022

In this episode, we talk with Dr. Jennifer Brown about the results of the ALPINE trial comparing zanubrutinib to ibrutinib for the treatment of CLL. 

emerging treatments for advanced BILIARY TRACT carcinoma

Released October 7, 2022

In this episode, we talk with Dr. Howard Lim about current and emerging systemic treatments for advanced, unresectable BTCs. 

precision medicine series ep12: Biomarkers for the treatment of breast cancer

Released September 16, 2022

In this episode, we talk with Dr. David Cescon about diagnostic, prognostic, and predictive biomarkers for the treatment of breast cancer. 

COVID-19 Prophylaxis Ep4: IMMUNOCOMPROMISED Patients

Released August 19, 2022

In this episode, we talk with Dr. Juthaporn Cowan about COVID-19 pre-exposure prophylaxis for immunocompromised patients. 

COVID-19 Prophylaxis Ep3: Patients with CANCER

Released August 16, 2022

In this episode, we talk with Dr. Dimas Yusuf about COVID-19 pre-exposure prophylaxis for patients with cancer

COVID-19 Prophylaxis Ep2: Patients with hematological malignancies

Released July 12, 2022

In this episode, we talk with Dr. Laurie Sehn about COVID-19 pre-exposure prophylaxis for patients with hematological malignancies. 

COVID-19 Prophylaxis Ep1: A pharmacist perspective (French)

Released July 7, 2022

In this episode, we talk with Dr. Annick Dufour about the pharmacist's perspective around COVID-19 prophylaxis for our most vulnerable populations. 

UROTHELIAL CARCINOMA: EV301 trial

Released June 16, 2022

In this episode, we talk with Dr. Nimira Alimohamed about the results of the EV-301 trial presented at ASCO 2022 for the treatment of advanced urothelial carcinoma. 

IMMUNOTHERAPY for cervical cancer

Released May 24, 2022

In this episode we talk with Dr. James Bentley about immunotherapy and biomarker testing for metastatic cervical cancer.

IMMUNOTHERAPY IN HNSCC SERIES ep3: ROLE OF THE MEDICAL ONCOLOGIST

Released May 19, 2022

In this episode, we talk with Dr. Martin Smoragiewicz about the medical oncologist’s role in managing patients with HNSCC, and how immunotherapies fit in to their practice

precision medicine series ep11: parp inhibitors as maintenance therapy in ovarian cancer

Released May 2, 2022

In this episode, we talk with Dr. Anna Tinker about the development of a pan-Canadian consensus paper on the selection and use of PARP inhibitors for first-line maintenance treatment in ovarian cancer. 

immunotherapy in HNSCC EP2: SURGICAL ONCOLOGY 

Released April 25, 2022

In this episode, we talk with Dr. Antoine Eskander about PD-L1 testing for HNSCC from a surgical oncologist's perspective.

immunotherapy in HNSCC EP1: PD-L1 Testing 

Released April 4, 2022

In this episode, we talk with Dr. Matthew Cecchini about PD-L1 testing for HNSCC from a pathologist's perspective.

triple negative breast cancer: immunotherapies & biomarkers

Released March 21, 2022

In this episode, we talk with Dr Stephen Chia about the use of biomarkers to determine which patients with TNBC can benefit from immunotherapy.

prophylaxiE de la covid-19 ep5: introduction (francais)

Released March 21, 2022

In this fifth episode of the series, we talk with Dr Alex Carignan about immunization against COVID-19 and how we can protect our most vulnerable populations who are not able to mount a sufficient antibody response to vaccination. (In French) 

prE- and Post- covid-19 prophylaxis ep4: HEMATOLOGIC MALIGNANCIES

Released March 14, 2022

In this fourth episode of the series, we talk with Dr. Carolyn Owen about immunization against COVID-19 and protecting patients with hematologic malignancies who are not able to mount a sufficient antibody response to vaccination. 

prE- and Post- covid-19 prophylaxis ep3: A PhARMACIST PERSPECTIVE

Released March 11, 2022

In this third episode of the series, we talk with Ajit Johal about immunization against COVID-19 and the pharmacist's role in protecting our most vulnerable populations who are not able to mount a sufficient antibody response to vaccination. 

Zanubrutinib for the Treatment of Waldenström’s Macroglobulinemia

Released March 8, 2022

In this episode, we discuss the use of zanubrutinib for the treatment of Waldenström’s Macroglobulinemia with Dr. Constantine Tam and Dr. Carolyn Owen.

prE- and Post- covid-19 prophylaxis ep2: SOLID ORGAN TRANSPLANT

Released March 8, 2022

In this second episode of the series, we talk with Dr. Zain Chagla about protecting patients with solid organ transplantation from COVID-19.  

prE- and Post- covid-19 prophylaxis ep1: introduction

Released March 8, 2022

In this introductory episode, we talk with Dr. Brian Conway about immunization against COVID-19 and how we can protect our most vulnerable populations who are not able to mount a sufficient antibody response to vaccination.  

precision medicine series ep10: Biomarkers in gastrointestinal malignancies

Released February 7, 2022

In this episode, we talk with Dr. Rosalyn Juergens, a medical oncologist at the Juravinski Cancer Center in Hamilton, ON, about the evolving biomarker landscape in gastrointestinal malignancies and some of the advantages and challenges of implementing and accessing biomarker testing. 

precision medicine series ep9: DEBATE - Is PARP inhibitor maintenance therapy in first-line BRCA mutated ovarian cancer a curative-intent strategy?

Released January 10, 2022

This episode features a debate between Dr. Taymaa May, Surgical Scientist at the University Health Network and Professor at the University of Toronto and Dr. James Bently, Professor and Head of the Department of Obstetrics and Gynaecology at Dalhousie University on whether first-line maintenance therapy with PARP inhibitors can be considered a curative strategy in patients with advanced, BRCA-mutated epithelial ovarian cancer.

precision medicine series ep8: importance of BRCA testing for advanced epthelial ovarian cancer

Released December 7, 2021 

In this episode, we talk with Dr. Janice Kwon, Professor, Department of Obstetrics and Gynecology, University of British Columbia, BC and Dr. Alon Altman, Gynecologist Oncologist and Professor, University of Manitoba, MB about the importance of BRCA testing for advanced epithelial ovarian cancer. 

precision medicine series ep7: GENETIC TESTING IN PROSTATE cancer

Released November 29, 2021 

In this episode, we talk with Dr. Neil Fleshner, Professor of Surgery at the University of Toronto about the evolution and uptake of genetic testing in prostate cancer.  

precision medicine in oncology series ep6: BIOMARKER TESTING IN Colorectal cancer

Released November 26, 2021 

In this episode, we talk with Dr. Raul Gonzalez, Professor of Pathology at Harvard Medical School about genomic testing methodology, particularly for mismatch repair deficiency, as well as potential emerging biomarkers for metastatic colorectal cancer.  

precision medicine series ep5: metastatic Colorectal cancer

Released September 27, 2021 

In this episode, we talk with Dr. Sharlene Gill, Professor of Medicine at the University of British Columbia about the current standards for molecular testing in metastatic colorectal cancer.

Lung cancer screening in western canada

Released September 2, 2021 

In this episode, we talk with Dr. Stephen Lam, Professor of Medicine at the University of British Columbia, and Dr. Rakesh Patel, General Practitioner at the Silverado Medical Clinic in Calgary. 

DEPISTAGE DU CANCER DU POUMON EN QUEBEC

Released September 2, 2021 

On discute avec Dre Nicole Bouchard, Pneumologue au département de médecine de l’Université de Sherbrooke, et Dr Richard Dumouchel, Omnipraticien à la Clinique médicale du Coteau, à Saint-Jean-sur-Richelieu, Québec. 

Lung Cancer SCreening in ONTARIO

Released September 2, 2021 

In this episode, we talk with Dr. Donna Maziak, thoracic surgeon and surgical oncologist at the Ottawa Hospital, and Chantal Bornais, nurse navigator at the Ottawa Hospital. 

Lung Cancer SCreening in canada

Released September 1, 2021 

In this episode, we talk with Dr. Paul Wheatley Price, Associate Professor at the University of Ottawa and Dr. Jeffery Habert, General Practitioner in Thornhill, ON about lung cancer screening programs in Canada.

TREATMENT OF R/R HODGKIN'S LYMPHOMA

Released July 13, 2021 

In this episode, we talk with Dr. John Kuruvilla, Associate Professor of Medicine at the University of Toronto and Princess Margaret Hospital in Toronto about novel therapies for the treatment of Hodgkin's lymphoma.  

Precision Medicine Series EP 4: ACCESS TO GENOMIC PROFILING IN QC 

Released July 13, 2021 

In this fourth episode of the series, we talk with Barry Stein, President & CEO of Colorectal Cancer Canada about genomic testing in colorectal cancer. The full CGP report can be found here: https://www.impactmedicom.com/publications/reports

Precision Medicine Series EP 3: ACCESS TO GENOMIC PROFILING IN QC

Released April 21, 2021 

In this third episode of the series, we talk with Dr. Brandon Sheffield, anatomical pathologist at William Osler Health System in Brampton, ON about CGP from a laboratory perspective. The full CGP report can be found here: https://www.impactmedicom.com/publications/reports

MYTHBUSTERS SERIES Ep3: Addressing COVID-19 Vaccine Hesitancy

Released April 28, 2021 

This series is aimed at health care professionals who are at the front lines of vaccine delivery to help address common sources of misinformation around COVID-19 vaccines. In the third episode, we talk with Dr. Raywat Deonandan, Associate Professor & Epidemiologist at the University of Ottawa.

MYTHBUSTERS SERIES Ep2: Addressing COVID-19 Vaccine Hesitancy

Released April 21, 2021 

This series is aimed at health care professionals who are at the front lines of vaccine delivery to help address common sources of misinformation around COVID-19 vaccines. In the second episode, we talk with Dr. Lynora Saxinger, world-renowned infectious disease specialist based at the University of Alberta.

MYTHBUSTERS SERIES Ep1 PART 1: Addressing COVID-19 Vaccine Hesitancy

Released April 14, 2021 

This series is aimed at health care professionals who are at the front lines of vaccine delivery to help address common sources of misinformation around COVID-19 vaccines. In the first episode, we talk with Dr. Kelly Grindrod, Associate Professor at the University of Waterloo, about common sources of misinformation and how these can be addressed. This episode is divided into 2 parts. 

MYTHBUSTERS SERIES Ep1 PART 2: Addressing COVID-19 Vaccine Hesitancy

Released April 14, 2021 

This series is aimed at health care professionals who are at the front lines of vaccine delivery to help address common sources of misinformation around COVID-19 vaccines. In the first episode, we talk with Dr. Kelly Grindrod, Associate Professor at the University of Waterloo, about common sources of misinformation and how these can be addressed. This is the second part of Episode 1. 

Precision Medicine Series Ep 2: ACCESS TO GENOMIC PROFILING IN BC

Released March 24, 2021 

In this second episode of the series, we discuss the BC OncoPanel, challenges for including CGP in lab budgets, the information exchange needed between stakeholders to accelerate access, and how the CGP report can provide decision makers with a framework for implementing CGP testing. The full CGP report can be found here: https://www.impactmedicom.com/publications/reports

Precision Medicine Series Ep 1: Introduction with Dr. Sandeep Sedhev

Released Feb 19, 2021 

In this first episode of the series, we discuss the importance of CGP as a critical tool for treating patients with advanced solid tumors. We discuss a CGP report, which was developed to aid Canadian decision makers in the prioritization of funding access to CGP testing in patients with solid tumors. The full CGP report can be found here: https://www.impactmedicom.com/publications/reports

BTK INHIBITORS FOR THE TREATMENT OF CLL: Are they all the same?

Released Feb 5, 2021 

We discuss the use of Bruton's Tyrosine Kinase (BTK) inhibitors for the treatment of patients with chronic lymphocytic leukemia (CLL) with Dr. Carolyn Owen, hemato-oncologist at the Tom Baker Cancer Center in Calgary, Alberta. A press release on results of the ELEVATE-RR trial can be found here: https://www.cancernetwork.com/view/acalabrutinib-meets-primary-end-point-versus-ibrutinib-in-previously-treated-high-risk-cll  

Chronic Lymphocytic Leukemia (CLL): How do we Manage Patients During COVID-19?

Released Oct 28, 2020 

We discuss the management of patients with chronic lymphocytic leukemia (CLL) with Dr. Michel Pavic, who is a Medical Oncologist and Chief of the Hemato-Oncology department at the Centre intégré universitaire de santé et de services sociaux de l’Estrie – Centre Hospitalier Universitaire de Sherbrooke and an assistant professor in the Faculty of Medicine and Health Sciences at the Université de Sherbrooke. The Canadian recommendations for treating CLL during COVID-19 can be found here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339858/pdf/conc-27-e332.pdf

Virtual Patient ManagemenT: MANAGING PATIENTS WITH Inflammatory Arthritis

Released October 23, 2020

We discuss the virtual management of patients with inflammatory arthritis with Rheumatologist, Dr. Janet Pope, who is a Professor of Medicine in the Division of Rheumatology, Epidemiology and Biostatistics at the University of Western Ontario. 

The opioid epidemic in Canada: What can we do?

Released October 22, 2020

Pharmacists, Dr. Ross Tsuyuki (professor and chair of the Department of Pharmacology in the Faculty of Medicine and Dentistry at the University of Alberta) and Mark Barnes (Owner of Respect Rx  Pharmacies in Ottawa), discuss the opioid epidemic in Canada and use of naloxone to prevent death from opioid overdose. The naloxone guidelines for pharmacists can be found here: https://journals.sagepub.com/doi/pdf/10.1177/1715163520949973

covid-19: playing sports safely 

Released October 14, 2020

Dr. Ray Deonandan, Canadian epidemiologist, assistant director, and associate professor at the University of Ottawa, discusses how to more safely play sports with others during the COVID-19 pandemic. 

**Funding for our podcast provided by Seagen, BeiGene, AstraZeneca, Merck, Alexion

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